UV Radiation Affects Water Permeability in Stratum Corneum Lipids

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A 2014 study summary in the Journal of the American Academy of Dermatology (vol 70, no 5, p.AB157) investigating the connection between skin lipid permeability and radiation from sunlight. The authors find that sunlight disrupts these lipids which then disrupts the body’s own skin barrier protection process.

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We investigated the effects of UV radiation on the water permeability in model SC [Stratum Corneum] lipid films.

UV-C radiation breaks chemical bonds in SC lipid films and diminishes their structural order, thereby greatly increasing the permeability of water in SC lipids.

The direct disruption of the SC lipid permeability is an additional mechanism UV radiation can manifest its disruption effects on skin barrier function.


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