The Use of Endogenous Antioxidants to Improve Photoprotection.
The skin possesses an elaborate antioxidant defence system to deal with UV-induced oxidative stress. However, excessive exposure to UV can overwhelm the cutaneous antioxidant capacity, leading to oxidative damage and ultimately to... premature skin aging.
Although treatments with single components of the antioxidant system were successful against a wide variety of photodamage, the balance between the different antioxidants in the skin is very important. In some studies, it was found that too much of a single component could even have deleterious effects.