Air pollution, Autophagy and Skin Aging


From the Journal of Investigative Dermatology (vol 138, no 9, p.B24), a 2018 study summary discussing the negative effects of air pollution on autophagy – one of our bodies’ natural cell regeneration processes. The authors conclude that air pollution damages Fibroblasts – the cells in our connective tissue that produce collagen and other fibers – which, in turn, disrupts the autophagy process.

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Ambient particulate matter (PM) represents an environmental threat to which millions of people worldwide are exposed. Adverse effects of PM on human health have been reported, but its effect on skin aging has not been widely studied. Autophagy is… one of the survival mechanisms for cells during extrinsic and intrinsic stress.

Conclusion: Fibroblasts [cells in connective tissue that produce collagen and other fibers] exposed to PM showed signs of aging which indicate that air pollution might influence skin aging.

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